Scientific Exploration Of Probiotic Activity And Inactivation
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Author : Olian Li
Update time : 2024-08-15 14:35:28
（1） Active probiotics
Active probiotics refer to probiotic strains that can maintain vitality, continue to grow and reproduce after entering the human body. These strains have excellent acid and bile salt resistance, can resist the digestion of gastric acid and bile, successfully colonize the intestine, and exert their probiotic effects. By regulating the balance and function of the gut microbiota, active probiotics produce beneficial metabolites such as short chain fatty acids and antimicrobial peptides, thereby promoting immune health and maintaining a stable gut state.
（2） Inactivated probiotics
In contrast, inactivated probiotics are strains that have undergone specific treatments (such as heating) to lose their growth and reproductive abilities. Although they are unable to carry out metabolic activities, they still retain some bioactive substances such as cell wall components, nucleic acids, and proteins. Inactivated probiotics mainly exert probiotic effects by releasing these cell wall components, metabolites, and other active substances. They can directly stimulate the intestinal barrier, promote intestinal health, and are not affected by stomach acid and bile.
（3） Mechanism of action
1. Active probiotics: rely on their own vitality and metabolic products to regulate the gut microbiota, inhibit the growth of harmful bacteria, and promote the reproduction of beneficial bacteria.
2. Inactivated probiotics: mainly exert probiotic effects by releasing cell wall components and metabolites, and their mechanism does not depend on the growth and reproduction of the strain.
（4） How to scientifically choose probiotic products？
When choosing probiotic products, comprehensive consideration should be given to individual needs and health conditions. For individuals who require rapid improvement of their gut microbiota, active probiotics may be more suitable; For individuals who prioritize product stability and safety, or those with sensitive gastrointestinal environments, inactivating probiotics is a more ideal choice. In addition, attention should also be paid to the type, content, production process, and availability of third-party testing reports of the product's bacterial strains. These pieces of information help ensure that you are purchasing high-quality, suitable probiotic products for yourself.
（5） Why choose Healthdream？
Healthdream collaborates closely with nearly 200 top factories and laboratories, especially with probiotic laboratories such as UniLab in Shanghai, to jointly develop new varieties and technologies of probiotics. Moreover, with a strict quality management system (ISO9001&ISO22000 certification), Healthdream ensures that probiotics can efficiently colonize and function in the human body through scientific formulas, and adopts advanced production processes to effectively improve their tolerance to stomach acid and bile, ensuring their activity in complex intestinal environments.
Therefore,choosing Healthdream means choosing trust and efficiency！
Active probiotics refer to probiotic strains that can maintain vitality, continue to grow and reproduce after entering the human body. These strains have excellent acid and bile salt resistance, can resist the digestion of gastric acid and bile, successfully colonize the intestine, and exert their probiotic effects. By regulating the balance and function of the gut microbiota, active probiotics produce beneficial metabolites such as short chain fatty acids and antimicrobial peptides, thereby promoting immune health and maintaining a stable gut state.
（2） Inactivated probiotics
In contrast, inactivated probiotics are strains that have undergone specific treatments (such as heating) to lose their growth and reproductive abilities. Although they are unable to carry out metabolic activities, they still retain some bioactive substances such as cell wall components, nucleic acids, and proteins. Inactivated probiotics mainly exert probiotic effects by releasing these cell wall components, metabolites, and other active substances. They can directly stimulate the intestinal barrier, promote intestinal health, and are not affected by stomach acid and bile.
（3） Mechanism of action
1. Active probiotics: rely on their own vitality and metabolic products to regulate the gut microbiota, inhibit the growth of harmful bacteria, and promote the reproduction of beneficial bacteria.
2. Inactivated probiotics: mainly exert probiotic effects by releasing cell wall components and metabolites, and their mechanism does not depend on the growth and reproduction of the strain.
（4） How to scientifically choose probiotic products？
When choosing probiotic products, comprehensive consideration should be given to individual needs and health conditions. For individuals who require rapid improvement of their gut microbiota, active probiotics may be more suitable; For individuals who prioritize product stability and safety, or those with sensitive gastrointestinal environments, inactivating probiotics is a more ideal choice. In addition, attention should also be paid to the type, content, production process, and availability of third-party testing reports of the product's bacterial strains. These pieces of information help ensure that you are purchasing high-quality, suitable probiotic products for yourself.
（5） Why choose Healthdream？
Healthdream collaborates closely with nearly 200 top factories and laboratories, especially with probiotic laboratories such as UniLab in Shanghai, to jointly develop new varieties and technologies of probiotics. Moreover, with a strict quality management system (ISO9001&ISO22000 certification), Healthdream ensures that probiotics can efficiently colonize and function in the human body through scientific formulas, and adopts advanced production processes to effectively improve their tolerance to stomach acid and bile, ensuring their activity in complex intestinal environments.
Therefore,choosing Healthdream means choosing trust and efficiency！
